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Clinical Trials: Vanderbilt Diabetes Center

7 trials found: Print This Page for Your Doctor

A Multicenter, Randomized, Double-Blind, Placebo-controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Dapagliflozin as an Add-on to Insulin Therapy in Subjects with Type 1 Diabetes Mellitus (IRB No. 150035)

  • Principal Investigator
    Shichun Bao
    Medicine
  • Summary
    The purpose of this study is to evaluate the safety and effectiveness of dapagliflozin at two dose levels in addition to insulin in patients with type 1 diabetes. This study is for persons with type 1 diabetes whose hemoglobin A1C level is too high and who need to get better control of their blood sugar. You may be able to be in the study if: You have type 1 diabetes and are 21 - 75 years of age, and treated with insulin. If you can be in the study, you will receive lab tests and the study medication at no charge to you. You will be paid for your time.
  • Contact
    Dianne Riello
    615-322-4549
    dianne.riello@Vanderbilt.Edu

Evaluation of Dermal Myelinated Fibers in Patients with Diabetic Polyneuropathy (IRB No. 100772)

  • Principal Investigator
    Amanda Peltier
    Neurology
  • Summary
    The purpose of the study is to learn more about the nerve damage that happens in diabetes.
  • Contact
    Kay J. Artibee
    615-936-8102
    kay.j.artibee@Vanderbilt.edu

High Fat Diet: Oxidative Effects & Cardiovascular Risk (IRB No. 071325)

  • Principal Investigator
    Heidi J. Silver
    Gastroenterology, Medicine
  • Summary
    The purpose of this study is to evaluate the effects of different types of fat on weight loss and risk factors associated with getting type 2 diabetes and heart disease.
  • Contact
    Taren Spence, RD
    615-936-0985
    taren.spence@vanderbilt.edu

Insulin Detemir in Obesity Management (IDIOM) (IRB No. 101424)

  • Principal Investigator
    Kevin D. Niswender
    Medicine, Diabetes, Endocrinology and Metabolism
  • Summary
    The purpose of this study is to investigate the effect of insulin detemir on body weight, brain function, and other metabolic measures relevant to type 2 diabetes mellitus.
  • Contact
    Wanda Snead
    615-936-1625
    wanda.snead@Vanderbilt.Edu

Oral Insulin For Prevention of Diabetes In Relatives At Risk For Type 1 Diabetes Mellitus (IRB No. 070030)

  • Principal Investigator
    William E. Russell
    Pediatrics, Pediatric Endocrinology
  • Summary
    This study is designed to see if oral insulin will delay or prevent type one diabetes in blood relatives that have been determined to be at risk.
  • Contact
    Margo M. Black
    615-936-8638 or 888-884-8638
    diabetesresearch@vanderbilt.edu

Systolic Blood Pressure Intervention Trial (SPRINT) (IRB No. 101157)

  • Principal Investigator
    Julia B. Lewis
    Medicine, Nephrology
  • Summary
    The purpose of this study is to see whether treating blood pressure aggressively will reduce the rate of heart disease and stroke, memory decline or worsening of kidney disease in adults over the age of 55 years, who already have high blood pressure with no history of diabetes or stroke. If you meet study qualifications and wish to take part in the study you will receive the following at no cost:
    • blood pressure medications
    • Physical exams
    • Lab tests
    • Memory tests
    • EKG's (electrocardiograms)
    If you would like to learn more, please contact: Nephrology Clinical Trials Center Julia Lewis or Mohammed Sika 615-936-1179 or 888-537-0497 hypertension
  • Contact
    Mohammed Sika
    615-936-2630
    Mohammed.Sika@vanderbilt.edu

TrialNet Natural History Study of the Development of Type One Diabetes (IRB No. 060684)

  • Principal Investigator
    William E. Russell
    Pediatrics, Pediatric Endocrinology
  • Summary
    The purpose of this study is to learn more about how Type 1 Diabetes occurs. Close blood relatives of someone with diabetes are at greater risk for type 1 diabetes than others. We are screening only close blood relatives of people with type 1 diabetes. This includes brothers, sisters, parents, children, cousins, aunts, uncles, and grandchildren. If you are found to be at high risk for developing type 1 diabetes, you might qualify for research studies that might delay or prevent the onset of type 1 diabetes.
  • Contact
    Margo M. Black
    615-936-8638 or 888-884-8638
    diabetesresearch@vanderbilt.edu