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Kidney Transplant Selection Criteria

Vanderbilt Kidney Transplant Selection Criteria as of May 2025

What: Selection criteria are the requirements your transplant team uses to decide if a transplant is the best and safest option for someone with end stage renal disease.

Selection Criteria:

Indications:

  • Patient has end-stage renal disease (ESRD) as evidenced by measured (actual urinary collection) creatinine clearance level or calculated GFR (Cockcroft-Gault or other reliable formula) less than or equal to 20ml/min or initiation of dialysis.

Relative Contraindications

  • Age ≥ 75  
  • Morbid obesity (BMI ≥ 35)  
  • Inadequate bladder/urinary conduit
  • Frailty
  • Multiple medical comorbidities
  • History of Malignancy or active malignancy  
  • Psycho-Social issues
  • Oxalosis (may require liver/kidney transplantation)
  • Cirrhosis 

Absolute Contraindications: 

  • Morbid obesity (BMI ≥ 45)
  • Active systemic infection
  • Active substance abuse  
  • Sickle cell disease  
  • Significant psychiatric illness likely to interfere with adherence
  • HIV – CD4 count < 200 or detectable viral load
  • Severe cardiac disease
  • Severe peripheral vascular disease/Vascular calcifications
  • Active Malignancy, see AST recommendations for wait intervals
  • Hepatitis B infection (detectable viral load)
  • Decompensated cirrhosis
  • Medical non-adherence
  • Active wounds
  • COPD/Oxygen dependence
  • Pulmonary Hypertension PAS ≥ 70
  • Inadequate insurance 

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