Kidney Transplant Selection Criteria
Vanderbilt Kidney Transplant Selection Criteria as of May 2025
What: Selection criteria are the requirements your transplant team uses to decide if a transplant is the best and safest option for someone with end stage renal disease.
Selection Criteria:
Indications:
- Patient has end-stage renal disease (ESRD) as evidenced by measured (actual urinary collection) creatinine clearance level or calculated GFR (Cockcroft-Gault or other reliable formula) less than or equal to 20ml/min or initiation of dialysis.
Relative Contraindications:
- Age ≥ 75
- Morbid obesity (BMI ≥ 35)
- Inadequate bladder/urinary conduit
- Frailty
- Multiple medical comorbidities
- History of Malignancy or active malignancy
- Psycho-Social issues
- Oxalosis (may require liver/kidney transplantation)
- Cirrhosis
Absolute Contraindications:
- Morbid obesity (BMI ≥ 45)
- Active systemic infection
- Active substance abuse
- Sickle cell disease
- Significant psychiatric illness likely to interfere with adherence
- HIV – CD4 count < 200 or detectable viral load
- Severe cardiac disease
- Severe peripheral vascular disease/Vascular calcifications
- Active Malignancy, see AST recommendations for wait intervals
- Hepatitis B infection (detectable viral load)
- Decompensated cirrhosis
- Medical non-adherence
- Active wounds
- COPD/Oxygen dependence
- Pulmonary Hypertension PAS ≥ 70
- Inadequate insurance