Vanderbilt Endocrinology

Education

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Research Description

Publications

Dai, C, Chung, IJ, Krantz, SB. Increased erythropoiesis in polycythemia vera is associated with increased erythroid progenitor proliferation and increased phosphorylation of Akt/PKB. Exp Hematol, 33(2), 152-8, 2005

Dai, C, Chung, IJ, Krantz, SB. In human immature BFU-E tumor necrosis factor-alpha not only downregulates CDK6 but also directly produces apoptosis which is prevented by stem cell factor. Exp Hematol, 32(10), 911-7, 2004

Xu MJ, Sui SW, Zhao RX, Dai CH, Krantz SB, Zhao ZZ. PTP-MEG2 is Activated in Polycythemia Vera Erythroid Progenitor Cells and is Essential for Growth and Expansion of Erythroid Cells.. Blood, 102, 4354-4360, 2003

Dai, C, Chung, IJ, Jiang, S, Price, JO, Krantz, SB. Reduction of cell cycle progression in human erythroid progenitor cells treated with tumour necrosis factor alpha occurs with reduced CDK6 and is partially reversed by CDK6 transduction. Br J Haematol, 121(6), 919-27, 2003

Dai, C, Krantz, SB. Increased expression of the INK4a/ARF locus in polycythemia vera. Blood, 97(11), 3424-32, 2001

Dai, C, Krantz, SB. Interferon gamma induces upregulation and activation of caspases 1, 3, and 8 to produce apoptosis in human erythroid progenitor cells. Blood, 93(10), 3309-16, 1999

Dai CH, Wickrema A, Krantz SB. Human erythroid progenitor cells: purification and culture. In volume 4; Primary hematopoietic cells. Ed. M. Koller. Kluwer Academic Publishers, Dordrecht, The Netherlands, pp 259-286, 1999

Dai, CH, Price, JO, Brunner, T, Krantz, SB. Fas ligand is present in human erythroid colony-forming cells and interacts with Fas induced by interferon gamma to produce erythroid cell apoptosis. Blood, 91(4), 1235-42, 1998

Taniguchi, S, Dai, CH, Krantz, SB. Specific binding of interferon-gamma to high affinity receptors on human erythroid colony-forming cells. Exp Hematol, 25(3), 193-8, 1997

Dai, CH, Krantz, SB, Sawyer, ST. Polycythemia vera. V. Enhanced proliferation and phosphorylation due to vanadate are diminished in polycythemia vera erythroid progenitor cells: a possible defect of phosphatase activity in polycythemia vera. Blood, 89(10), 3574-81, 1997

Taniguchi, S, Dai, CH, Price, JO, Krantz, SB. Interferon gamma downregulates stem cell factor and erythropoietin receptors but not insulin-like growth factor-I receptors in human erythroid colony-forming cells. Blood, 90(6), 2244-52, 1997

Dai CH, Krantz SB, Kollar K, Price JO. Stem cell factor can overcome inhibition of highly purified human burst-forming units-erythroid by interferon r. J Cell Physiol, 165, 323-332, 1995

Muta K, Krantz SB, Bondurant M, Dai CH. Stem cell factor retards differentiation of normal human erythroid progenitor cells while stimulaing proliferation. . Blood , 86, 572-580,, 1995

Dai CH, Krantz SB, Koury ST, Kollar K. Polycythemia vera. IV. Specific binding of stem cell factor to normal and polycythemia vera highly purifed erythroid progenitor cells. . Br. J Hematol. , 88: , 497-505,, 1994

Dai CH, Krantz SB, Green WF, Gilbert HS. Polycythemia vera. III. Burst-forming units-erythroid (BFU-E) response to stem cell factor and c-kit receptor expression. . Br. J Hematol , 86:, 12-21, , 1994

Wickrema, A, Koury, ST, Dai, CH, Krantz, SB. Changes in cytoskeletal proteins and their mRNAs during maturation of human erythroid progenitor cells. J Cell Physiol, 160(3), 417-26, 1994

Krantz SB, Dai CH, Mean RT, Horn ST, Gilbert HS. . Blood burst forming units-erythroid in PV are hypersensitive to IL-3. In molecular biology of hematopoiesis, . Edited by Abraham NG, Konwalinka G, Marks P, Sachs L and Tavassoli M. Intercept Ltd, Andover,, Vol 2, , pp 555-565, 1992

Dai CH, Krantz SB. . Vanadate mimics the effect of stem cell factor on highly purified human burst-forming units-erythroid in vitro, but not the effect of erythropoietin. Exp. Hematol , 20:, 1055-1060, , 1992

Dai CH, Krantz SB, Dessypris EN, Means RT, Horn ST. Polycythemia vera. II Hypersensitivity of bone marrow erythroid, granulocyte-macrophage and megakaryocyte progenitor cells to interleukin-3 and granulocyte-macrophage colony-stimulating factor.. Blood, 80: , 891-899,, 1992

Sawada K, Krantz SB, Dai CH, Sato N, Ieko M: . Transitional change of colony stimulating factor requirements for erythroid progenitors. J Cell Physiol.. J Cell Physiol, 149: , 1-8, , 1991

Dai, CH, Krantz, SB, Means, RT, Horn, ST, Gilbert, HS. Polycythemia vera blood burst-forming units-erythroid are hypersensitive to interleukin-3. J Clin Invest, 87(2), 391-6, 1991

Dai CH, Krantz SB, Zsebo KM: . Human burst-forming units-erythroid need direct interaction with stem cell factor for further development. Blood, 78:, 2493-2497, 1991

Dai CH, Krantz SB, Means RT, Horn AT, Gilbert HS. Increased sensitivity of polycythemia vera blood burst-forming units-erythroid to interleukin-3. In Assoc. Am. Phys. , Vol CIII, 249-257, 1990

Sawada K, Krantz SB, Dai CH. . Purification of human blood burst-forming units-erythroid and demonstration of the evolution of erythropoietin receptors. J Cell Physiol. , 142:, 219-230, 1990

Chung IJ, Dai CH, Krantz SB. Stem Cell Factor Increases the Expression of FLIP Which Inhibits IFN_-induced Apoptosis in Human Erythroid Progenitor Cells. Blood , 101, 1324-1328, 2003