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"Evolutionarily conserved pathways for genome stability in yeast and human cells"
Munira Basrai, Ph.D.
Center for Cancer Research
National Cancer Institute
Dr. Basrai’s research focuses on the molecular mechanisms for faithful chromosome segregation in budding yeast and human. Her group has characterized the role of centromere binding proteins, and provided mechanistic insights into how acetylation, phosphorylation and ubiquitination of centromeric histone H3 variant, Cse4, and H4 regulate chromosome segregation. Her group also developed a genome-wide screen that led to the identification of evolutionarily conserved genes that are haploinsufficient for chromosome segregation. These studies provide critical insights into genome instability that is frequently observed in many cancers.
Any students, staff, or faculty are welcome to attend, Q&A session afterward for students and faculty members to ask the speaker any questions.
Refreshments/tea time service at 3:45 pm.